WEIL Nutrition Corner®

WEIL Nutrition Corner®

Should You Take Peptides?

Learn more about peptides - what they are, why your body already produces peptides, and our takes on whether or not you should consider supplementing with more.

Dr. Andrew Weil & Diana Weil's avatar
Dr. Andrew Weil & Diana Weil
Sep 23, 2026
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Happy Wednesday! Today, we are tackling peptides - a very popular trend right now. Find out everything you need to know about peptides, including:

  • What peptides are

  • The different types

  • Who may benefit from them

  • Who should be cautious

  • Risks to consider

  • Our takes on whether or not we recommend peptides

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What Are Peptides?

Peptides are short chains of amino acids (basically mini-proteins). Your body naturally makes them, and they act as signals, telling cells what to do. Peptides themselves are fundamental to biology.

Examples of peptides you already have:

  • Insulin, which regulates blood sugar

  • Collagen peptides, which help with the structure of skin and joints

  • Growth hormone-related peptides, which signal growth and repair

Peptides are one of those topics where the marketing is way ahead of the evidence. Some are useful, some are neutral, and some are questionable, all depending on how they’re used.

What about supplemental peptides - and are they healthy?

You can supplement with peptides, and some are considered generally safe. Here are different types of peptides and how “healthy” they’re ranked as.

1. Generally safe / low-risk (when taken normally)

These peptides are ones you’ll see in foods or basic supplements, and are widely considered safe for most people:

  • Collagen peptides

  • Protein-derived peptides (like whey fragments)

Benefits:

  • May support skin, joints, and connective tissue

  • Basically function like a specialized protein source


2. Gray area (limited evidence)

Peptides marketed for fat loss, muscle growth, recovery, or anti-aging (e.g., BPC-157, CJC-1295, ipamorelin) may have some promising early research, but they are not well-studied in humans over the long-term, may not be FDA-approved, and dosing and purity can vary.


3. Medical peptides (for specific use)

Prescribed peptides (like insulin, GLP-1 drugs, etc.) are well-studied and used under medical supervision.


Who might benefit from peptide supplements?

Reasonable candidates include:

  • People with joint issues may find benefits from collagen peptides

  • People wanting extra protein support may benefit from collagen, though it is not a complete protein

  • Clinical cases under a doctor, such as hormone deficiencies or metabolic diseases


Who should be cautious or avoid peptides?

Be careful if:

  • You’re considering injectable peptides from online clinics

  • You’re expecting steroid-like muscle or fat loss effects

  • You have a hormone-sensitive condition (e.g., certain cancers)

  • You’re pregnant or breastfeeding

  • You’re already on medications affecting hormones

Especially avoid:

  • “Research peptides” sold online with no regulation

  • Anything promising rapid fat loss and muscle gain - this is a big red flag


What are some key risks of peptides?

If you are considering peptides, be aware of:

  • Lack of regulation - this can lead to contamination or incorrect dosing

  • Hormonal disruption, especially with growth hormone-related peptides

  • Unknown long-term effects

  • Cost vs. actual benefit is often not worth it

The more a peptide sounds like a shortcut to physique or anti-aging… the more skeptical you should be.


Interested in more topics like this? Try reading these posts:

Boosting Collagen Through Foods and Vitamin C + Collagen-Supporting Recommendations

Boosting Collagen Through Foods and Vitamin C + Collagen-Supporting Recommendations

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May 8
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Our Take on The Collagen Powder Trend and Why Green Tea Should Be Your Go-To Drink

Our Take on The Collagen Powder Trend and Why Green Tea Should Be Your Go-To Drink

Dr. Andrew Weil & Diana Weil
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May 7, 2025
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Is Bone Broth Healthy - and Worth the Price?

Is Bone Broth Healthy - and Worth the Price?

Dr. Andrew Weil & Diana Weil
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November 5, 2025
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Our Takes On Peptides

Now that you have the what, see what we say about peptides… Our Takes are for our VIP subscribers, so upgrade today to access our takes on peptides and the entire Our Takes library, including what we think about statins, drinking coffee on an empty stomach, the safety of canned tuna and more. Our 35% off Fall Sale is going on now - upgrade and save today!

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